Adrenorphin

• Description :

  Adrenorphin is a opioid octapeptide, acting as a potent agonist of μ-opioid receptor, with Ki of 12 nM.

• Product Name Alternative :

  Metorphamide

• UNSPSC :

  12352209

• Target :

  Opioid Receptor

• Type :

  Reference compound

• Related Pathways :

  GPCR/G Protein; Neuronal Signaling

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/Adrenorphin.html

• Purity :

  98.84

• Solubility :

  10 mM in H2O|DMSO : 50 mg/mL (ultrasonic)

• Smiles :

  CC(C)[C@@H](C(N)=O)NC([C@H](CCCNC(N)=N)NC([C@H](CCCNC(N)=N)NC([C@H](CCSC)NC([C@@H](NC(CNC(CNC([C@@H](N)CC1=CC=C(O)C=C1)=O)=O)=O)CC2=CC=CC=C2)=O)=O)=O)=O

• Molecular Formula :

  C44H69N15O9S

• Molecular Weight :

  984.18

• References & Citations :

  [1]Weber E, et al. Metorphamide: isolation, structure, and biologic activity of an amidated opioid octapeptide from bovine brain. Proc Natl Acad Sci U S A. 1983 Dec;80 (23) :7362-6.|[2]Yanase T, et al. Studies on adrenorphin in pheochromocytoma. J Clin Endocrinol Metab. 1987 Apr;64 (4) :692-7.

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  -80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• Isoform :

  μ Opioid Receptor/MOR

• CAS Number :

  [88377-68-8]