Adrenorphin

• Description:

  Adrenorphin is a opioid octapeptide, acting as a potent agonist of μ-opioid receptor, with Ki of 12 nM.

• Product Name Alternative:

  Metorphamide

• UNSPSC:

  12352209

• Target:

  Opioid Receptor

• Type:

  Reference compound

• Related Pathways:

  GPCR/G Protein; Neuronal Signaling

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/Adrenorphin.html

• Purity:

  98.84

• Solubility:

  10 mM in H2O|DMSO : 50 mg/mL (ultrasonic)

• Smiles:

  CC (C) [C@@H] (C (N) =O) NC ([C@H] (CCCNC (N) =N) NC ([C@H] (CCCNC (N) =N) NC ([C@H] (CCSC) NC ([C@@H] (NC (CNC (CNC ([C@@H] (N) CC1=CC=C (O) C=C1) =O) =O) =O) CC2=CC=CC=C2) =O) =O) =O) =O

• Molecular Formula:

  C44H69N15O9S

• Molecular Weight:

  984.18

• References & Citations:

  [1]Weber E, et al. Metorphamide: isolation, structure, and biologic activity of an amidated opioid octapeptide from bovine brain. Proc Natl Acad Sci U S A. 1983 Dec;80 (23) :7362-6.|[2]Yanase T, et al. Studies on adrenorphin in pheochromocytoma. J Clin Endocrinol Metab. 1987 Apr;64 (4) :692-7.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• Isoform:

  μ Opioid Receptor/MOR

• CAS Number:

  88377-68-8