Thiorphan

• UNSPSC Description:

  Thiorphan is a selective NEP (neprilysin) inhibitor with an IC50 of 6.9 nM[1].

• Target Antigen:

  Neprilysin

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/thiorphan.html

• Purity:

  99.67

• Solubility:

  DMSO : 250 mg/mL (ultrasonic)

• Smiles:

  SCC(C(NCC(O)=O)=O)CC1=CC=CC=C1

• Molecular Weight:

  253.323

• References & Citations:

  [1]Whyteside AR, Turner AJ. Human neprilysin-2 (NEP2) and NEP display distinct subcellular localisations and substrate preferences. FEBS Lett. 2008 Jul 9;582(16):2382-6.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -20°C (Powder, protect from light)

• Clinical Information:

  No Development Reported

• CAS Number:

  76721-89-6