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Interferon alfa-2b

CAT: 0804-HY-P99666-01Size: 1 mLDry Ice: NoHazardous: No
CAT#:0804-HY-P99666-01Size:1 mL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Interferon alfa-2b is a type I interferon that activates novel genes and exerts potent antiviral and antiproliferative activity on target cells. Signaling by Interferon alfa-2b requires receptor-dependent activation of Stat1 and Stat2 to form a heterodimeric STAT that binds to the DNA-binding protein IRF-9 (p48) and forms ISGF-3 (IFN-stimulated gene factor 3) . The driver genes are then further activated by ISGF-3 to achieve antiviral function[1].
UNSPSC
12352203
Target
IFNAR
Type
Inhibitory Antibodies
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Infection; Cancer
Assay Protocol
https://www.medchemexpress.com/interferon-alfa.html
Purity
95.0
Solubility
10 mM in DMSO
Smiles
[Interferonalfa-2b]
Molecular Weight
(20.7 kDa)
References & Citations
[1]Park C, et al. Immune response in Stat2 knockout mice. Immunity. 2000 Dec;13 (6) :795-804.
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4°C for 2 years, do not freeze
Scientific Category
Inhibitory Antibodies
Clinical Information
No Development Reported

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