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Prazosin Hydrochloride

CAT: 0572-TRC-P702325-100MGSize: 100 mgDry Ice: NoHazardous: No
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CAT#:0572-TRC-P702325-100MGSize:100 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
19237-84-4
Synonyms
Prazosin Hydrochloride; Terazosin Hydrochloride Dihydrate Imp. K (EP) as Hydrochloride; [4-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-1-piperazinyl]-2-furanyl-methanone hydrochloride (1:1); 1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-(2-furanylcarbonyl)-piperazine monohydrochloride; 1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-(2-furoyl)-piperazine monohydrochloride; 2-[4-(2-Furoyl)piperazin-1-yl]-4-amino-6,7-dimethoxyquinazoline hydrochloride; Adversuten; Adverszuten; Alpress LP; CP 12299-1; Deprazolin; Duramipress; Eurex; Furazosin hydrochloride; Hypovase; Hypovasole; Minipress; NSC 292810; Peripress; Pratsiol; Prazosin hydrochloride; Sinetens; Terazosin Hydrochloride Dihydrate Imp. K (EP); Terazosin Imp. K (EP); Terazosin Hydrochloride Dihydrate Impurity K as Hydrochloride; Terazosin Impurity K as Hydrochloride
Hazard Statement
Harmful if swallowed
Purity
>95% (HPLC)
Smiles
Cl.COc1cc2nc(nc(N)c2cc1OC)N3CCN(CC3)C(=O)c4occc4
Molecular Formula
C19 H21 N5 O4 . Cl H
Molecular Weight
419.86
InChI
InChI=1S/C19H21N5O4.ClH/c1-26-15-10-12-13(11-16(15)27-2)21-19(22-17(12)20)24-7-5-23(6-8-24)18(25)14-4-3-9-28-14;/h3-4,9-11H,5-8H2,1-2H3,(H2,20,21,22);1H
Additionnal Information
IUPAC name: [4-(4-amino-6,7-dimethoxyquinazolin-2-yl)piperazin-1-yl]-(furan-2-yl)methanone;hydrochloride
Shipping Conditions
Room Temperature
Storage Conditions
-20°C

Chemical Information

Prazosin Hydrochloride

Prazosin Hydrochloride is a synthetic piperazine derivative with hypotensive antiadrenergic properties, Prazosin Hydrochloride reduces peripheral resistance and relaxes vascular smooth muscles as a selective adrenergic alpha-1 antagonist by a mechanism not completely known. It is used in the treatment of heart failure, hypertension, pheochromocytoma, Raynaud's syndrome, prostatic hypertrophy, and urinary retention. (NCI04)

CAS Number19237-84-4
PubChem CID68546
IUPAC Name[4-(4-amino-6,7-dimethoxyquinazolin-2-yl)piperazin-1-yl]-(furan-2-yl)methanone;hydrochloride
Molecular FormulaC19H22ClN5O4
Molecular Weight419.9
Topological Polar Surface Area107
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count8
Rotatable Bond Count4
Heavy Atom Count29
Formal Charge0
Complexity544
SMILES
COC1=C(C=C2C(=C1)C(=NC(=N2)N3CCN(CC3)C(=O)C4=CC=CO4)N)OC.Cl
InChI
InChI=1S/C19H21N5O4.ClH/c1-26-15-10-12-13(11-16(15)27-2)21-19(22-17(12)20)24-7-5-23(6-8-24)18(25)14-4-3-9-28-14;/h3-4,9-11H,5-8H2,1-2H3,(H2,20,21,22);1H
InChIKey
WFXFYZULCQKPIP-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of Prazosin Hydrochloride
CAS: 19237-84-4
CID: 68546
Formula: C19H22ClN5O4
MW: 419.9
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight419.9
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count8
Rotatable Bond Count4
Exact Mass419.1360319
Monoisotopic Mass419.1360319
Topological Polar Surface Area107 Ų
Heavy Atom Count29
Formal Charge0
Complexity544
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count2
Compound Is CanonicalizedYes

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CatalogName
T1050-01Prazosin hydrochloride
HY-B0193A-01Prazosin (hydrochloride)
HY-B0193AS-01Prazosin-d8 (hydrochloride)
HY-B0193AR-01Prazosin (hydrochloride) (Standard)
RM-T182611-01Terazosin EP Impurity K; Prazosin Hydrochloride
P5661-50Prazosin Hydrochloride (Alpress LP, Eurex, Hypovase, Minipress, 1- (4-Amino-6,7-dimethoxy-2-quinazolinyl) -4- (2-furanylcarbonxyl) piperazine, Hydrochloride) discontinued. See 217694
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