Mal-PEG6-PFP ester

• Description:

  Mal-PEG6-PFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

• UNSPSC:

  12352005

• Hazard Statement:

  H302, H315, H319, H335

• Target:

  PROTAC Linkers

• Type:

  Reference compound

• Related Pathways:

  PROTAC

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/mal-peg6-pfp-ester.html

• Purity:

  96.18

• Solubility:

  DMSO : 100 mg/mL (ultrasonic)

• Smiles:

  O=C(OC1=C(F)C(F)=C(F)C(F)=C1F)CCOCCOCCOCCOCCOCCOCCN2C(C=CC2=O)=O

• Molecular Formula:

  C25H30F5NO10

• Molecular Weight:

  599.50

• Precautions:

  H302, H315, H319, H335

• References & Citations:

  [1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -20°C (Powder, stored under nitrogen)

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• Isoform:

  Alkyl/ether Linkers; PEG Linkers

• CAS Number:

  [1599486-33-5]