Wright's stain

• Description:

  Wright's stain is a composite cell stain that mainly binds to intracellular nucleic acids, proteins and other components through thiazine dyes (such as methylene blue) and eosin. Wright's stain is pH-dependent (optimal pH 6.4-6.7) and achieves cell morphology resolution by differentially staining the cytoplasm and nucleus. Under alkaline conditions, thiazine dyes bind to nucleic acids to form purple, and acidic eosin binds to cytoplasmic proteins to form red, which can form contrasting cell morphological features. Wright's stain can clearly display the fine structures of blood cells and bone marrow cells (such as nuclear chromatin and granules) and quickly evaluate cell morphological abnormalities[1][2].

• UNSPSC:

  12171500

• Hazard Statement:

  H302, H317, H319, H402

• Target:

  Fluorescent Dye

• Type:

  Dye Reagents

• Related Pathways:

  Others

• Field of Research:

  Others

• Assay Protocol:

  https://www.medchemexpress.com/wright-s-stain.html

• Purity:

  95.0

• Solubility:

  10 mM in DMSO

• Smiles:

  [Wright's stain]

• Precautions:

  H302, H317, H319, H402

• References & Citations:

  [1]N Kutaish. Automated staining of bone marrow and peripheral blood by a modified Wright's technic. Am J Clin Pathol. 1982 Mar;77 (3) :319-20.|[2]Chen L, et al. A Novel and Rapid Smear Cytomorphology Detection Strategy Based on Upconversion Nanoparticles Immunolabeling Integrated with Wright's Staining for Accurate Diagnosis of Leukemia. Int J Nanomedicine. 2023 Sep 13;18:5213-5224.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  4°C (Powder, protect from light)

• Scientific Category:

  Dye Reagents

• Clinical Information:

  No Development Reported

• CAS Number:

  68988-92-1