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Wright's stain

CAT: 0804-HY-W088068-01Size: 5 gDry Ice: NoHazardous: No
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CAT#:0804-HY-W088068-01Size:5 g
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Wright's stain is a composite cell stain that mainly binds to intracellular nucleic acids, proteins and other components through thiazine dyes (such as methylene blue) and eosin. Wright's stain is pH-dependent (optimal pH 6.4-6.7) and achieves cell morphology resolution by differentially staining the cytoplasm and nucleus. Under alkaline conditions, thiazine dyes bind to nucleic acids to form purple, and acidic eosin binds to cytoplasmic proteins to form red, which can form contrasting cell morphological features. Wright's stain can clearly display the fine structures of blood cells and bone marrow cells (such as nuclear chromatin and granules) and quickly evaluate cell morphological abnormalities[1][2].
CAS Number
68988-92-1
UNSPSC
12171500
Hazard Statement
H302, H317, H319, H402
Target
Fluorescent Dye
Type
Dye Reagents
Related Pathways
Others
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/wright-s-stain.html
Purity
95.0
Solubility
10 mM in DMSO
Smiles
[Wright'sstain]
Precautions
H302, H317, H319, H402
References & Citations
[1]N Kutaish. Automated staining of bone marrow and peripheral blood by a modified Wright's technic. Am J Clin Pathol. 1982 Mar;77 (3) :319-20.|[2]Chen L, et al. A Novel and Rapid Smear Cytomorphology Detection Strategy Based on Upconversion Nanoparticles Immunolabeling Integrated with Wright's Staining for Accurate Diagnosis of Leukemia. Int J Nanomedicine. 2023 Sep 13;18:5213-5224.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Dye Reagents
Clinical Information
No Development Reported

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