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Paricalcitol

CAT: 0804-HY-50919-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-50919-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Paricalcitol, a vitamin D analogue, is a vitamin D receptor agonist, used for the prevention and treatment of secondary hyperparathyroidism (excessive secretion of parathyroid hormone) associated with chronic renal failure.
CAS Number
131918-61-1
UNSPSC
12352211
Hazard Statement
H225, H319
Target
VD/VDR
Type
Reference compound
Related Pathways
Vitamin D Related/Nuclear Receptor
Applications
COVID-19-immunoregulation
Field of Research
Metabolic Disease; Cancer
Assay Protocol
https://www.medchemexpress.com/Paricalcitol.html
Purity
99.96
Solubility
DMSO : 100 mg/mL (ultrasonic) |Ethanol : 12.5 mg/mL (ultrasonic)
Smiles
C[C@]([C@]([C@H](C)/C=C/[C@H](C)C(C)(C)O)([H])CC1)(CCC/2)[C@]1([H])C2=C\C=C3C[C@@H](O)C[C@H](O)C/3
Molecular Formula
C27H44O3
Molecular Weight
416.64
Precautions
H225, H319
References & Citations
[1]Martinez-Moreno JM, et al. In vascular smooth muscle cells paricalcitol prevents phosphate-induced Wnt/beta-catenin activation. Am J Physiol Renal Physiol. 2012 Aug 8.|[2]Meems LM, et al. The vitamin D receptor activator paricalcitol prevents fibrosis and diastolic dysfunction in a murine model of pressure overload. J Steroid Biochem Mol Biol. 2012 Jul 16;132 (3-5) :282-289.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light, stored under nitrogen)
Scientific Category
Reference compound1
Clinical Information
Launched

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