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Tenuifolin

CAT: 0804-HY-N0702-01Size: 1 mgDry Ice: NoHazardous: No
CAT#:0804-HY-N0702-01Size:1 mg
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Description
Tenuifolin is effective and has a protective action. Tenuifolin inhibits β-secretase decreases Aβ protein secretion, suppresses Aβ25-35 secretion, and subsequently caspase-3 and caspase-9 become active. Tenuifolin's ability to lower AChE activity, increase at the same time, increase the ability of the upper glands, and improve the ability to read and remember. Research on tenuifolin's potential for use in urinary disease (AD) [1][2].
CAS Number
[20183-47-5]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Beta-secretase; Cholinesterase (ChE)
Type
Natural Products
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/tenuifolin.html
Concentration
10mM
Purity
99.73
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
OC[C@@]1(CC[C@]2(C(O)=O)[C@@]3([H])CC(C)(C)CC2)C3=CC[C@@]4([H])[C@]1(CC[C@]5([H])[C@@]4(C[C@H](O)[C@H](O[C@]([C@@H]([C@@H](O)[C@@H]6O)O)([H])O[C@@H]6CO)[C@@]5(C)C(O)=O)C)C
Molecular Formula
C36H56O12
Molecular Weight
680.82
Precautions
H302, H315, H319, H335
References & Citations
[1]Ki-Yeol Yoo, et al. Terpenoids as Potential Anti-Alzheimer’s Disease Therapeutics. Molecules 2012, 17 (3), 3524-3538|[2]Wang L, et al. Protective effects of tenuifolin isolated from Polygala tenuifolia Willd roots on neuronal apoptosis and learning and memory deficits in mice with Alzheimer's disease. Food Funct. 2019 Nov 1;10 (11) :7453-7460.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, protect from light)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
AChE

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