Anthraquinone

CAT: 0804-HY-N0354-01Size: 25 gDry Ice: NoHazardous: No
CAT#:0804-HY-N0354-01Size:25 g
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Anthraquinone is used as a precursor for dye formation and agrochemicals, existing in different organisms, such as bacteria, fungi, plants, and some animals. Anthraquinone has biological activities: anticancer, antiinflammatory, diuretic, antiarthritic, antifungal, antibacterial, antimalarial and antioxidant. Anthraquinone also plays an important role in the primary metabolism of plants by acting on the electron transport chain through the inhibition of energy transfer in the photosynthetic process. Anthraquinone can intercalates into DNA and inhibits the topoisomerase II (topo II) enzyme, resulting in cell death via Apoptosis[1][2][3][4].
CAS Number
[84-65-1]
UNSPSC
12352005
Hazard Statement
H317, H350
Target
Apoptosis; Topoisomerase; Virus Protease
Type
Natural Products
Related Pathways
Anti-infection; Apoptosis; Cell Cycle/DNA Damage
Applications
COVID-19-anti-virus
Field of Research
Cancer; Infection; Metabolic Disease; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/anthraquinone.html
Purity
99.97
Solubility
DMSO : 2 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C1C2=C(C=CC=C2)C(C3=CC=CC=C13)=O
Molecular Formula
C14H8O2
Molecular Weight
208.22
Precautions
H317, H350
References & Citations
[1]Diaz-Munoz G, et al. Anthraquinones: an overview[J]. Studies in natural products chemistry, 2018, 58: 313-338.|[2]Yen G C, Duh P D, Chuang D Y. Antioxidant activity of anthraquinones and anthrone[J]. Food chemistry, 2000, 70 (4) : 437-441.|[3]Andersen DO, et al. In vitro virucidal activity of selected anthraquinones and anthraquinone derivatives. Antiviral Res. 1991 Sep;16 (2) :185-96. |[4]Barnard D L, et al. Evaluation of the antiviral activity of anthraquinones, anthrones and anthraquinone derivatives against human cytomegalovirus[J]. Antiviral research, 1992, 17 (1) : 63-77.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported

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