Anthraquinone

• UNSPSC Description:

  Anthraquinone is used as a precursor for dye formation and agrochemicals, existing in different organisms, such as bacteria, fungi, plants, and some animals. Anthraquinone has biological activities: anticancer, antiinflammatory, diuretic, antiarthritic, antifungal, antibacterial, antimalarial and antioxidant. Anthraquinone also plays an important role in the primary metabolism of plants by acting on the electron transport chain through the inhibition of energy transfer in the photosynthetic process. Anthraquinone can intercalates into DNA and inhibits the topoisomerase II (topo II) enzyme, resulting in cell death via Apoptosis[1][2][3][4].

• Target Antigen:

  Apoptosis; Topoisomerase; Virus Protease

• Type:

  Natural Products

• Related Pathways:

  Anti-infection;Apoptosis;Cell Cycle/DNA Damage

• Applications:

  COVID-19-anti-virus

• Field of Research:

  Cancer; Infection; Metabolic Disease; Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/anthraquinone.html

• Purity:

  99.97

• Solubility:

  DMSO : 2 mg/mL (ultrasonic;warming;heat to 60°C)

• Smiles:

  O=C1C2=C(C=CC=C2)C(C3=CC=CC=C13)=O

• Molecular Weight:

  208.216

• References & Citations:

  [1]Diaz-Munoz G, et al. Anthraquinones: an overview[J]. Studies in natural products chemistry, 2018, 58: 313-338.|[2]Yen G C, Duh P D, Chuang D Y. Antioxidant activity of anthraquinones and anthrone[J]. Food chemistry, 2000, 70(4): 437-441.|[3]Andersen DO, et al. In vitro virucidal activity of selected anthraquinones and anthraquinone derivatives. Antiviral Res. 1991 Sep;16(2):185-96. |[4]Barnard D L, et al. Evaluation of the antiviral activity of anthraquinones, anthrones and anthraquinone derivatives against human cytomegalovirus[J]. Antiviral research, 1992, 17(1): 63-77.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Clinical Information:

  No Development Reported

• CAS Number:

  84-65-1