EWP 815

• Description :

  EWP 815 is a disulfiram analogue, is a potent inhibitor of Ins (1,4) P2 phosphatase and Ins (1,4,5) P3 5-phosphatase. EWP 815 also inhibits enzyme dopamine β-hydroxylase activity[1][2].

• CAS Number :

  [20231-01-0]

• UNSPSC :

  12352005

• Target :

  Dopamine β-hydroxylase; Phosphatase

• Type :

  Reference compound

• Related Pathways :

  Metabolic Enzyme/Protease

• Applications :

  Metabolism-sugar/lipid metabolism

• Field of Research :

  Others

• Assay Protocol :

  https://www.medchemexpress.com/ewp-815.html

• Purity :

  98.25

• Solubility :

  DMSO : 50 mg/mL (ultrasonic)

• Smiles :

  S=C(N1CCN(C)CC1)SSC(N2CCN(C)CC2)=S

• Molecular Formula :

  C12H22N4S4

• Molecular Weight :

  350.59

• References & Citations :

  [1]Fowler CJ, et al. Inhibition of inositol 1,4,5-trisphosphate 5-phosphatase by micromolar concentrations of disulfiram and its analogues. Biochem J. 1993 Feb 1;289 (Pt 3) (Pt 3) :853-9. |[2]Carlsson A, et al. On the beta-hydroxylation of (+-) -alpha-methyldopamine in vivo. Eur J Pharmacol. 1968 Dec;5 (1) :85-92.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  4°C (Powder, protect from light)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported