Levosimendan (Standard)

• UNSPSC Description:

  Levosimendan (Standard) is the analytical standard of Levosimendan. This product is intended for research and analytical applications. Levosimendan (Simsndan; OR-1259) is a calcium sensitiser used in the management of acutely decompensated congestive heart failure.

• Target Antigen:

  Autophagy; Phosphodiesterase (PDE); Potassium Channel

• Type:

  Reference Standards

• Related Pathways:

  Autophagy;Membrane Transporter/Ion Channel;Metabolic Enzyme/Protease

• Field of Research:

  Cardiovascular Disease

• Assay Protocol:

  https://www.medchemexpress.com/levosimendan-standard.html

• Smiles:

  O=C1C[C@@H](C)C(C2=CC=C(N/N=C(C#N)/C#N)C=C2)=NN1

• Molecular Weight:

  280.28

• References & Citations:

  [1]Nieminen, M.S., et al., Levosimendan: current data, clinical use and future development. Heart Lung Vessel, 2013. 5(4): p. 227-245.|[2]Papp, Z., et al., Levosimendan: molecular mechanisms and clinical implications: consensus of experts on the mechanisms of action of levosimendan. Int J Cardiol, 2012. 159(2): p. 82-7.|[3]Landoni, G., et al., Effects of levosimendan on mortality and hospitalization. A meta-analysis of randomized controlled studies. Crit Care Med, 2012. 40(2): p. 634-46.

• Shipping Conditions:

  Room temperature

• CAS Number:

  141505-33-1