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Tafluposide

CAT: 0804-HY-123363Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-123363Size:1 Each
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Description
Tafluposide (F-11782) is a DNA topoisomerase inhibitor. Tafluposide has antitumor activity[1].
CAS Number
179067-42-6
Product Name Alternative
F-11782
UNSPSC
12352005
Target
Topoisomerase
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/tafluposide.html
Smiles
O=C1OC[C@@]2([C@@H](C3=C([C@H]([C@]21[H])C4=CC(OC)=C(C(OC)=C4)OP(O)(O)=O)C=C5OCOC5=C3)O[C@H]6[C@H](OC(COC7=C(C(F)=C(C(F)=C7F)F)F)=O)[C@@H](OC(COC8=C(C(F)=C(C(F)=C8F)F)F)=O)[C@H]9[C@H](O6)CO[C@@H](C)O9)[H]
Molecular Formula
C45H35F10O20P
Molecular Weight
1116.71
References & Citations
[1]Sargent JM, et al. Ex vivo effects of the dual topoisomerase inhibitor tafluposide (F 11782) on cells isolated from fresh tumor samples taken from patients with cancer. Anticancer Drugs. 2003 Jul;14 (6) :467-73.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 1

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