Nudifloramide

• Description:

  Nudifloramide (2PY) is one of the end products of nicotinamide-adenine dinucleotide (NAD) degradation. Nudifloramide significantly inhibits poly (ADP-ribose) polymerase (PARP-1) activity in vitro[1].

• Product Name Alternative:

  2PY

• UNSPSC:

  12352005

• Hazard Statement:

  H302, H315, H319, H335

• Target:

  Endogenous Metabolite; PARP

• Type:

  Natural Products

• Related Pathways:

  Cell Cycle/DNA Damage; Epigenetics; Metabolic Enzyme/Protease

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Metabolic Disease

• Assay Protocol:

  https://www.medchemexpress.com/1-Methyl-6-oxo-1,6-dihydropyridine-3-carboxamide.html

• Purity:

  99.94

• Solubility:

  DMSO : 62.5 mg/mL (ultrasonic) |H2O : 33.33 mg/mL (ultrasonic)

• Smiles:

  O=C(C(C=C1)=CN(C)C1=O)N

• Molecular Formula:

  C7H8N2O2

• Molecular Weight:

  152.15

• Precautions:

  H302, H315, H319, H335

• References & Citations:

  [1]Rutkowski B, et al. N-methyl-2-pyridone-5-carboxamide: a novel uremic toxin? Kidney Int Suppl. 2003 May; (84) :S19-21.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category:

  Natural Products

• Clinical Information:

  No Development Reported

• Isoform:

  Human Endogenous Metabolite

• CAS Number:

  [701-44-0]