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Lenaldekar

CAT: 0804-HY-121662-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-121662-01Size:1 mg
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Description
Lenaldekar (LDK) inhibits human and murine T-cell expansiomn. Lenaldekar inhibits autoimmune T cell response. Lenaldekar also induces cancer cell apoptosis. Lenaldekar can be used for T-cell mediated autoimmune diseases research[1][2].
CAS Number
418800-15-4
Product Name Alternative
LDK
UNSPSC
12352005
Target
Apoptosis
Type
Reference compound
Related Pathways
Apoptosis
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/lenaldekar.html
Solubility
10 mM in DMSO
Smiles
C1(/C=N/NC2=C3N=CC=CC3=CC=C2)=CNC4=C1C=CC=C4
Molecular Formula
C18H14N4
Molecular Weight
286.33
References & Citations
[1]Cusick MF, et al. Human T cell expansion and experimental autoimmune encephalomyelitis inhibited by Lenaldekar, a small molecule discovered in a zebrafish screen. J Neuroimmunol. 2012 Mar;244 (1-2) :35-44.|[2]Ridges S, et al, et al. Zebrafish screen identifies novel compound with selective toxicity against leukemia. Blood. 2012 Jun 14;119 (24) :5621-31.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Alternative Products

CatalogName
GTR19174872-01Lenaldekar

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