Troxerutin

CAT: 0804-HY-N0139-01Size: 5 gDry Ice: NoHazardous: No
CAT#:0804-HY-N0139-01Size:5 g
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Description
Troxerutin, also known as vitamin P4, is a tri-hydroxyethylated derivative of natural bioflavonoid rutins which can inhibit the production of reactive oxygen species (ROS) and depress ER stress-mediated NOD activation.
CAS Number
[7085-55-4]
Product Name Alternative
Trihydroxyethylrutin
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
NOD-like Receptor (NLR)
Type
Natural Products
Related Pathways
Immunology/Inflammation
Applications
Cancer-programmed cell death
Field of Research
Cancer; Metabolic Disease; Inflammation/Immunology; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/Troxerutin.html
Purity
98.0
Solubility
DMSO : 100 mg/mL (ultrasonic; warming) |H2O : ≥ 50 mg/mL
Smiles
O=C1C(O[C@H]2[C@@H]([C@H]([C@@H]([C@@H](CO[C@H]3[C@@H]([C@@H]([C@H]([C@H](C)O3)O)O)O)O2)O)O)O)=C(C4=CC=C(OCCO)C(OCCO)=C4)OC5=CC(OCCO)=CC(O)=C15
Molecular Formula
C33H42O19
Molecular Weight
742.68
Precautions
H302, H315, H319, H335
References & Citations
[1]Lim KM, et al. Analysis of changes in microRNA expression profiles in response to the troxerutin-mediated antioxidant effect in human dermal papilla cells. Mol Med Rep. 2015 Aug;12 (2) :2650-60.|[2]Zhang Z, et al. Troxerutin Attenuates Enhancement of Hepatic Gluconeogenesis by Inhibiting NOD Activation-Mediated Inflammation in High-Fat Diet-Treated Mice. Int J Mol Sci. 2016 Dec 25;18 (1) . pii: E31.|[3]Badalzadeh R, et al. Beneficial effect of troxerutin on diabetes-induced vascular damages in rat aorta: histopathological alterations and antioxidation mechanism. Int J Endocrinol Metab. 2015 Apr 30;13 (2) :e25969.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
Launched

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