Products for Research Use Only

M5N36

CAT: 0804-HY-132578-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-132578-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
M5N36 is a potent and selective Cdc25C inhibitor with IC50 values of 0.15, 0.19, 0.06 µM for Cdc25A, Cdc25B, Cdc25C, respectively. M5N36 shows anti-proliferative activity and increases the expression of p-CDK1 and p-CDK2[1].
CAS Number
2832887-40-6
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Phosphatase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/m5n36.html
Purity
98.05
Solubility
DMSO : 25 mg/mL (ultrasonic)
Smiles
O=C1C(Cl)=C(C(C2=NC=CC=C21)=O)NC(C3=CN(N=N3)C4=CC=C(C=C4)CO)C
Molecular Formula
C20H16ClN5O3
Molecular Weight
409.83
Precautions
H302, H315, H319, H335
References & Citations
[1]Tao Y, et al. Discovery of potent and selective Cdc25 phosphatase inhibitors via rapid assembly and in situ screening of Quinonoid-focused libraries. Bioorg Chem. 2021 Oct;115:105254.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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BA8144-10M5N36