Acetylspiramycin

CAT: 0804-HY-B1916-01Size: 200 mgDry Ice: NoHazardous: No
CAT#:0804-HY-B1916-01Size:200 mg
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Description
Acetylspiramycin (Spiramycin B) is an effective oral macrolide antibiotic produced by Streptomyces, It can inhibit the splenic lymphocyte transformation induced by phytohemagglutinin (PHA), LPS (HY-D1056) and antigen, reduce the procoagulant activity of macrophages, have good antibacterial effect on gram-positive bacteria, and is also an effective antigenic insect agent, which can be used to fight parasitic infection[1][2][3][4].
CAS Number
[24916-51-6]
Product Name Alternative
Spiramycin B; Spiramycin II; Foromacidin B
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Antibiotic; Bacterial; Parasite
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/Acetylspiramycin.html
Purity
80.15
Solubility
DMSO : ≥ 50 mg/mL
Smiles
O[C@H]1[C@](O[C@H](C)[C@@H](O[C@@](O[C@@H](C)[C@@H]2O)([H])C[C@]2(O)C)[C@@H]1N(C)C)([H])O[C@@H]([C@H](C[C@H]([C@H](/C=C/C=C/C3)O[C@](CC[C@@H]4N(C)C)([H])O[C@@H]4C)C)CC=O)[C@H]([C@](CC(O[C@@H]3C)=O)([H])OC(C)=O)OC
Molecular Formula
C45H76N2O15
Molecular Weight
885.09
Precautions
H302, H315, H319, H335
References & Citations
[1]Min-Zhu Huang, et al. Therapeutic effects of acetylspiramycin and garlicin on cryptosporidiosis among drug users. Int J Parasitol Drugs Drug Resist|[2]Acetylspiramycin|[3]Li SY, et al. Acetylspiramycin and the immune system--II. Effects on lymphocyte proliferation, lymphokine production, delayed-type hypersensitivity and antibody production. Int J Immunopharmacol. 1986;8 (6) :657-664. |[4]Li SY, et al. Acetylspiramycin and the immune system. I. Effects of acetylspiramycin on phagocytosis by mouse macrophages in vitro and in vivo. Int J Immunopharmacol. 1985;7 (6) :881-8.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Launched
Isoform
Macrolide

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