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Cordycepin

CAT: 0804-HY-N0262-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-N0262-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Cordycepin (3'-Deoxyadenosine) is a nucleoside derivative and inhibits IL-1β-induced MMP-1 and MMP-3 expression in rheumatoid arthritis synovial fibroblasts (RASFs) in a dose-dependent manner[1]. Cordycepin kills Mycobacterium tuberculosis through hijacking the bacterial adenosine kinase[2].
CAS Number
73-03-0
Product Name Alternative
3'-Deoxyadenosine
UNSPSC
12352005
Hazard Statement
H301+H311+H331
Target
Antibiotic; Autophagy; Bacterial; MMP; TNF Receptor
Type
Natural Products
Related Pathways
Anti-infection; Apoptosis; Autophagy; Metabolic Enzyme/Protease
Applications
Cancer-Kinase/protease
Field of Research
Cancer; Infection; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/Cordycepin.html
Purity
99.95
Solubility
DMSO : 33.33 mg/mL (ultrasonic) |H2O : 2 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
OC[C@@H]1C[C@@H](O)[C@H](N2C=NC3=C2N=CN=C3N)O1
Molecular Formula
C10H13N5O3
Molecular Weight
251.25
Precautions
H301+H311+H331
References & Citations
[1]Noh EM, et al. Cordycepin inhibits IL-1beta-induced MMP-1 and MMP-3 expression in rheumatoid arthritis synovial fibroblasts. Rheumatology (Oxford) . 2009 Jan;48 (1) :45-8.|[2]Huang F, et al. Cordycepin kills Mycobacterium tuberculosis through hijacking the bacterial adenosine kinase. PLoS One. 2019 Jun 14;14 (6) :e0218449.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Natural Products
Clinical Information
Phase 2
Isoform
MMP-1; MMP-3

Alternative Products

CatalogName
T2993-01Cordycepin

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