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Imiquimod

CAT: 0400-SIH-601-50MGSize: 50 mgDry Ice: NoHazardous: No
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CAT#:0400-SIH-601-50MGSize:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Imiquimod activates the toll-like receptor7 /8 to secrete cytokines (primarily interferon-α (IFN-α), interleukin-6 (IL-6), and tumor necrosis factor-α (TNF-α)). It also has been shown to act as an adoside A1 and A2A receptor antagonist. It is clinically useful in the treatment of superficial basal cell carcinoma.
Description
TLR7/8 Agonist
CAS Number
99011-02-6
Product Name Alternative
1-Isobutyl-1H-imidazo[4,5-c]quinolin-4-amine; R837; S26308; TMX-101
UNSPSC
41116105
Type
Agonist
Source
Synthetic
Field of Research
Immunology | Innate Immunity | TLR Signaling | Neuroscience | Neurodegeneration | Alzheimer's Disease | Cell Signaling | Protein Phosphorylation | Serine / Threonine Kinases
Purity
>98% (HPLC) ; NMR: (Conforms)
Weight
0.005
Format
White powder
Solubility
May be dissolved in DMSO (2 mg/ml, warm)
Molecular Formula
C14H16N4
Molecular Weight
240.3
Precautions
Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
References & Citations
1. Kan Y., et al. (2012) J Virol. 86(19): 10338-10346.

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CatalogName
280414-01Imiquimod

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