SKA-31

• Background:

  SKA 31 is an activator of KCa3.1 and KCa2 channels. It has significant blood-pressure reducing activity in experimentally hypertensive mice, suggesting potassium channel activation as a therapeutic target for hypertension.

• Description:

  KCa3.1 and KCa2 channel activator

• Product Name Alternative:

  Naphtho[1,2-d]thiazol-2-ylamine

• UNSPSC:

  41116105

• Type:

  Activator

• Source:

  Synthetic

• Field of Research:

  Neuroscience | Neurotransmission | Neurotransmitter Receptors

• Purity:

  >98% (TLC) ; NMR (Conforms)

• Weight:

  0.005

• Format:

  Off-white powder

• Solubility:

  May be dissolved in DMSO (40mg/ml)

• Molecular Formula:

  C11H8N2S

• Molecular Weight:

  200.1

• Precautions:

  Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

• References & Citations:

  1. Sankaranarayanan A., et al. (2009) Mol Pharmacol. 75 (2): 281-295.

• CAS Number:

  40172-65-4