SKA-31

• Background :

  SKA 31 is an activator of KCa3.1 and KCa2 channels. It has significant blood-pressure reducing activity in experimentally hypertensive mice, suggesting potassium channel activation as a therapeutic target for hypertension.

• Description :

  KCa3.1 and KCa2 channel activator

• Product Name Alternative :

  Naphtho[1,2-d]thiazol-2-ylamine

• UNSPSC :

  41116105

• Type :

  Activator

• Source :

  Synthetic

• Field of Research :

  Neuroscience | Neurotransmission | Neurotransmitter Receptors

• Purity :

  >98% (TLC) ; NMR (Conforms)

• Weight :

  0.005

• Format :

  Off-white powder

• Solubility :

  May be dissolved in DMSO (40mg/ml)

• Molecular Formula :

  C11H8N2S

• Molecular Weight :

  200.1

• Precautions :

  Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

• References & Citations :

  1. Sankaranarayanan A., et al. (2009) Mol Pharmacol. 75 (2): 281-295.

• CAS Number :

  40172-65-4