Ponatinib

• Background:

  Ponatinib is a multi-targeted tyrosine kinase inhibitor. This agent also inhibits other tyrosine kinases including those associated with vascular endothelial growth factor receptors (VEGFRs) and fibroblast growth factor receptors (FGFRs).

• Description:

  Tyrosine Kinase Inhibitors

• Product Name Alternative:

  3- (2-Imidazo[1,2-b]pyridazin-3-ylethynyl) -4-methyl-N-[4-[ (4-methyl-1-piperazinyl) methyl]-3- (trifluoromethyl) phenyl]-benzamide, AP-24534

• UNSPSC:

  41116105

• Type:

  Inhibitor

• Source:

  Synthetic

• Field of Research:

  Cancer | Cancer Growth Inhibitors | Tyrosine Kinase Inhibitors

• Purity:

  >98% (HPLC) ; NMR (Conforms)

• Weight:

  0.005

• Format:

  Yellow powder

• Solubility:

  May be dissolved in DMSO (50 mg/ml); or Ethanol (25 mg/ml, warm)

• Molecular Formula:

  C29H27F3N6O

• Molecular Weight:

  532.6

• Precautions:

  Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

• CAS Number:

  943319-70-8