Bekanamycin

• Description:

  Bekanamycin (Kanamycin B) is an aminoglycoside antibiotic produced by Streptomyces kanamyceticus, against an array of Gram-positive and Gram-negative bacterial strain[1][2].

• Product Name Alternative:

  Kanamycin B

• UNSPSC:

  12352005

• Hazard Statement:

  H302, H315, H319, H335

• Target:

  Antibiotic; Bacterial

• Type:

  Natural Products

• Related Pathways:

  Anti-infection

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/Bekanamycin.html

• Purity:

  98.0

• Solubility:

  H2O : 100 mg/mL (ultrasonic)

• Smiles:

  O[C@H]1[C@](O[C@H]2[C@H](N)C[C@H](N)[C@@H](O[C@@]3([H])O[C@H](CN)[C@@H](O)[C@H](O)[C@H]3N)[C@@H]2O)([H])O[C@H](CO)[C@@H](O)[C@@H]1N

• Molecular Formula:

  C18H37N5O10

• Molecular Weight:

  483.51

• Precautions:

  H302, H315, H319, H335

• References & Citations:

  [1]Gao W, et al. Modulation of kanamycin B and kanamycin A biosynthesis in Streptomyces kanamyceticus viametabolic engineering. PLoS One. 2017 Jul 28;12 (7) :e0181971.|[2]Uchiyama T, et al. Presynaptic effects of bekanamycin at the frog neuromuscular junction. Reversibility by calcium and aminopyridines. Eur J Pharmacol. 1981 Jul 10;72 (4) :271-80.|[3]Fosso MY, et al. Synthesis and Bioactivities of Kanamycin B-Derived Cationic Amphiphiles. J Med Chem. 2015 Dec 10;58 (23) :9124-32.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category:

  Natural Products

• Clinical Information:

  Launched

• Isoform:

  Aminoglycoside

• CAS Number:

  [4696-76-8]