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Biotin (Standard)

CAT: 0804-HY-B0511R-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-B0511R-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Biotin (Standard) is the analytical standard of Biotin. Biotin, vitamin B7 and serves as a coenzyme for five carboxylases in humans, involved in the synthesis of fatty acids, isoleucine, and valine, and in gluconeogenesis. Biotin is necessary for cell growth, the production of fatty acids, and the metabolism of fats and amino acids[1][2][3].
CAS Number
58-85-5
Product Name Alternative
Vitamin B7 (Standard) ; Vitamin H (Standard) ; D-Biotin (Standard)
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Endogenous Metabolite; Reference Standards
Type
Reference Standards
Related Pathways
Metabolic Enzyme/Protease; Others
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/biotin-standard.html
Purity
98.05
Smiles
O=C(O)CCCC[C@@H]1SC[C@]([C@]1([H])N2)([H])NC2=O
Molecular Formula
C10H16N2O3S
Molecular Weight
244.31
Precautions
H302, H315, H319, H335
References & Citations
[1]Vadlapudi AD, et al. Biotin uptake by T47D breast cancer cells: functional and molecular evidence of sodium-dependent multivitamin transporter (SMVT) . Int J Pharm. 2013 Jan 30;441 (1-2) :535-43. |[2]Zempleni, et al. Biotin biochemistry and human requirements. J Nutr Biochem, 1999. 10 (3) : p. 128-38.|[3]Sghaier R, et al. Biotin attenuation of oxidative stress, mitochondrial dysfunction, lipid metabolism alteration and 7β-hydroxycholesterol-induced cell death in 158N murine oligodendrocytes. Free Radic Res. 2019 May;53 (5) :535-561. |[4]Mock, D.M.. Biotin status: which are valid indicators and how do we know? J Nutr, 1999. 129 (2S Suppl) : p. 498S-503S.|[5]Aldahmash BA, et al. Biotin amelioration of nephrotoxicity in streptozotocin-induced diabetic mice. Saudi J Biol Sci. 2015 Sep;22 (5) :564-9. |[6]Zempleni J, et al. Biotin. Biofactors. 2009 Jan-Feb;35 (1) :36-46.|[7]He P, et al. Dietary biotin deficiency decreased growth performance and impaired the immune function of the head kidney, spleen and skin in on-growing grass carp (Ctenopharyngodon idella) . Fish Shellfish Immunol. 2020 Feb;97:216-234.
Shipping Conditions
Room Temperature
Storage Conditions
4°C, sealed storage, away from light and moisture
Scientific Category
Reference Standards
Clinical Information
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