Bis(1-chloro-2-propyl) phosphate-d12

Bis(1-chloro-2-propyl) phosphate-d12

• CAS Number: 1870073-89-4
• UNSPSC Description: Bis(1-chloro-2-propyl) phosphate-d12 is deuterium labeled Bis(1-chloro-2-propyl) phosphate. Bis(1-chloro-2-propyl) phosphate (BCIPP) is a metabolite of organophosphate flame retardants (OPFR) that may alter energy metabolism by influencing the levels of steroid hormones, such as cortisol and cortisone. Bis(1-chloro-2-propyl) phosphate holds potential for research on metabolism-related diseases caused by environmental exposure[1][2].
• Target Antigen: Endogenous Metabolite; Isotope-Labeled Compounds
• Type: Reference compound
• Related Pathways: Metabolic Enzyme/Protease;Others
• Field of Research: Metabolic Disease
• Smiles: ClC([2H])(C(C([2H])([2H])[2H])(OP(OC(C([2H])([2H])[2H])(C([2H])(Cl)[2H])[2H])(O)=O)[2H])[2H]
• Molecular Weight: 263.12
• References & Citations: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.|[2]Ji Y, et al. Association between urinary organophosphate flame retardant diesters and steroid hormones: A metabolomic study on type 2 diabetes mellitus cases and controls. Sci Total Environ. 2021 Feb 20;756:143836.
• Shipping Conditions: Room temperature
• Clinical Information: Phase 2