Dopamine

CAT: 0804-HY-B0451-01Size: 10 mgDry Ice: NoHazardous: No
CAT#:0804-HY-B0451-01Size:10 mg
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Description
Dopamine is a catecholamine neurotransmitter that is produced in the substantia nigra, ventral tegmental area, and hypothalamus of the brain. Dopamine plays several important roles in the brain and body[1]. Dopamine acts through D2 dopamine receptors to induce endocytosis of VEGFR2, which is critical for promoting angiogenesis[1].
CAS Number
[51-61-6]
Product Name Alternative
ASL279 (free base)
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Dopamine Receptor; Endogenous Metabolite; Ferroptosis
Type
Natural Products
Related Pathways
Apoptosis; GPCR/G Protein; Metabolic Enzyme/Protease; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/dopamine.html
Purity
98.56
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
OC1=CC=C(CCN)C=C1O
Molecular Formula
C8H11NO2
Molecular Weight
153.18
Precautions
H302, H315, H319, H335
References & Citations
[1]Juárez Olguín H, et al. The Role of Dopamine and Its Dysfunction as a Consequence of Oxidative Stress. Oxid Med Cell Longev. 2016;2016:9730467.|[2]Basu S, et al. The neurotransmitter dopamine inhibits angiogenesis induced by vascular permeability factor/vascular endothelial growth factor. Nat Med. 2001 May;7 (5) :569-74.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, protect from light, stored under nitrogen)
Scientific Category
Natural Products
Clinical Information
Launched
Isoform
Microbial Metabolite
Citation 01
ACS Appl Mater Interfaces. 2025 Nov 26;17 (47) :64149-64167.|bioRxiv. 2023 Oct 13.|bioRxiv. 2025 Oct 22.|J Solid State Electrochem. 2025 Jan 17.|Nat Commun. 2025 Jan 2;16 (1) :323.|Biomed Pharmacother. 2019 Nov:119:109419.|bioRxiv. 2025 Oct 12.|Eur J Pharmacol. 2023 Dec 15:961:176174.|Eur J Pharmacol. 2025 Jul 5:998:177498.|Immunity. 2025 Aug 12:S1074-7613 (25) 00314-0.|Int J Mol Sci. 2022 Oct 17;23 (20) :12420.|Int J Nanomedicine. 2024 Jul 3:19:6717-6730.|Nat Commun. 2024 Feb 6;15 (1) :1122.|New J Chem. 03 Aug 2022.|Phytother Res. 2023 Aug;37 (8) :3296-3308.|Sci Adv. 2023 Jun 2;9 (22) :eadg3365.

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Alternative Products

CatalogName
MBS3614112-01Dopamine
N2930-15Nitroso-Dopamine (NO-Dopamine), Conjugated discontinued
170404DRD5 (Dopamine Receptor D5, D (5) Dopamine Receptor, D1beta Dopamine Receptor, D5 Dopamine Receptor, Dopamine 5 Receptor, Dopamine Receptor D5, DRD1B, D (1B) Dopamine Receptor, D1b Dopamine Receptor, D1b Receptor, DBDR, Dopamine Receptor 5, DRD1L2, Hd5dr, Dopamine d1b Receptor, Dopamine D5 Receptor, Dopamine Receptor D1B)
170400DRD1 (DRD1, D (1A) Dopamine Receptor, D1a Dopamine Receptor, Dopamine d-1 Receptor, Dopamine Receptor d1a, DRD1A, DADR, Dopamine d1a Receptor, Dopamine Receptor D1, Dopamine 1 Receptor, Dopamine Type 1 Receptor, D-1 Dopamine Receptor, D1 Dopamine Receptor, D1a Receptor, Dopamine D1 Receptor)
170389Dopamine Receptor D4 (DRD4, D (4) Dopamine Receptor, D4DR, D (2C) Dopamine Receptor, D4 Dopamine Receptor, Dopamine Receptor D4, Dopamine 4 Receptor, Dopamine D4 Receptor) discontinued
170403DRD4 (Dopamine Receptor D4, D (4) Dopamine Receptor, D4DR, D (2C) Dopamine Receptor, D4 Dopamine Receptor, Dopamine 4 Receptor, Dopamine D4 Receptor)
170386Dopamine D2 Receptor (DRD2, D2 Dopamine Receptor, D2R, Dopamine Receptor D2 Isoform, Dopamine 2 Receptor, D (2) Dopamine Receptor, D2DR, Dopamine D2 Receptor, Dopamine Receptor D2)
047609Dopamine D5R/DRD5 (Dopamine D5 Receptor)
45462-01Dopamine Hydrochloride (Dopamine HCl) extrapure, 98%
170388Dopamine Receptor D1 (Extracellular Domain) (D (1A) Dopamine Receptor, D1a Dopamine Receptor, Dopamine d-1 Receptor, Dopamine Receptor d1a, DRD1, DRD1A, DADR, Dopamine d1a Receptor, Dopamine Receptor D1, Dopamine 1 Receptor, Dopamine Type 1 Receptor, D-1 Dopamine Receptor, D1 Dopamine Receptor, D1a Receptor)

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