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Dopamine

CAT: 0804-HY-B0451-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-B0451-01Size:10 mg
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Description
Dopamine is a catecholamine neurotransmitter that is produced in the substantia nigra, ventral tegmental area, and hypothalamus of the brain. Dopamine plays several important roles in the brain and body[1]. Dopamine acts through D2 dopamine receptors to induce endocytosis of VEGFR2, which is critical for promoting angiogenesis[1].
CAS Number
51-61-6
Product Name Alternative
ASL279 (free base)
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Dopamine Receptor; Endogenous Metabolite; Ferroptosis
Type
Natural Products
Related Pathways
Apoptosis; GPCR/G Protein; Metabolic Enzyme/Protease; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/dopamine.html
Purity
98.56
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
OC1=CC=C(CCN)C=C1O
Molecular Formula
C8H11NO2
Molecular Weight
153.18
Precautions
H302, H315, H319, H335
References & Citations
[1]Juárez Olguín H, et al. The Role of Dopamine and Its Dysfunction as a Consequence of Oxidative Stress. Oxid Med Cell Longev. 2016;2016:9730467.|[2]Basu S, et al. The neurotransmitter dopamine inhibits angiogenesis induced by vascular permeability factor/vascular endothelial growth factor. Nat Med. 2001 May;7 (5) :569-74.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, protect from light, stored under nitrogen)
Scientific Category
Natural Products
Clinical Information
Launched
Isoform
Microbial Metabolite
Citation 01
ACS Appl Mater Interfaces. 2025 Nov 26;17 (47) :64149-64167.|bioRxiv. 2023 Oct 13.|bioRxiv. 2025 Oct 22.|J Solid State Electrochem. 2025 Jan 17.|Nat Commun. 2025 Jan 2;16 (1) :323.|Biomed Pharmacother. 2019 Nov:119:109419.|bioRxiv. 2025 Oct 12.|Eur J Pharmacol. 2023 Dec 15:961:176174.|Eur J Pharmacol. 2025 Jul 5:998:177498.|Immunity. 2025 Aug 12:S1074-7613 (25) 00314-0.|Int J Mol Sci. 2022 Oct 17;23 (20) :12420.|Int J Nanomedicine. 2024 Jul 3:19:6717-6730.|Nat Commun. 2024 Feb 6;15 (1) :1122.|New J Chem. 03 Aug 2022.|Phytother Res. 2023 Aug;37 (8) :3296-3308.|Sci Adv. 2023 Jun 2;9 (22) :eadg3365.