Adhesamine

• Description :

  Adhesamine, dumbbell-shaped molecule, activates MAPK/FAK pathway. Adhesamine promotes adhesion and growth of mammalian cells. Adhesamine accelerates the differentiation and improves the survival of mice hippocampal neurons in primary culture[1].

• CAS Number :

  [462605-73-8]

• UNSPSC :

  12352005

• Target :

  FAK

• Type :

  Reference compound

• Related Pathways :

  Protein Tyrosine Kinase/RTK

• Applications :

  Neuroscience-Neuromodulation

• Field of Research :

  Neurological Disease

• Assay Protocol :

  https://www.medchemexpress.com/adhesamine.html

• Purity :

  98.04

• Solubility :

  DMSO : 1 mg/mL (ultrasonic; warming; heat to 80°C)

• Smiles :

  O=CC1=C(N=C(SC)N=C1N2CC[N+]3(CC[N+]4(CC3)CCN(CC4)C5=NC(SC)=NC(Cl)=C5C=O)CC2)Cl.[Cl-].[Cl-]

• Molecular Formula :

  C24H32Cl4N8O2S2

• Molecular Weight :

  670.51

• References & Citations :

  [1]Hoshino M, et al. Adhesamine, a new synthetic molecule, accelerates differentiation and prolongs survival of primary cultured mouse hippocampal neurons. Biochem J. 2010 Mar 29;427 (2) :297-304.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  4°C (Powder, sealed storage, away from moisture)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported