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GNLY Protein

CAT: 0247-OPPA02310-2UGSize: 2 µgDry Ice: NoHazardous: No
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CAT#:0247-OPPA02310-2UGSize:2 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Gene Aliases
LAG2, NKG5, LAG-2, D2S69E, TLA519
Gene ID
10578
Accession Number
NP_006424.2
Reactivity
Human
Target
GNLY is part of the SAPLIP family and is located in the cytotoxic granules of T cells, which are discharged upon antigen stimulation. GNLY is localized in cytotoxic granules of cytotoxic T lymphocytes and natural killer cells, and it has antimicrobial activity against M. tuberculosis and other organisms. GNLY is an antimicrobial protein that kills intracellular pathogens. GNLY is active against a wide range of microbes, including Gram-positive and Gram-negative bacteria, fungi, and parasites. Kills Mycobacterium tuberculosis. GNLY Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 159 amino acids.
Type
Protein
Source
E. Coli
Sequence
MGSSHHHHHHSSGLVPRGSHMMEGLVFSRLSPEYYD LARAHLRDEEKSCPCLAQEGPQGDLLTKTQELGRDYR TCLTIVQKLKKMVDKPTQRSVSNAATRVCRTGRSRWR DVCRNFMRRYQSRVTQGLVAGETAQQICEDLRLCIPS TGPLGSHHHHHH
Purification
The GNLY is purified by proprietary chromatographic techniques.
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Concentration
1 mg/ml (prior to lyophilization)
Format
Lyophilized// from a concentrated (1 mg/ml) solution containing no additives. Physical appearance:// Sterile filtered white powderPhysical appearance:// Sterile filtered white powder
Reconstitution
2Please prevent freeze-thaw cycles.//
Molecular Weight
18.1 kDa
Notes
Formerly GWB-BSP494
Protein Length
Recombinant
NCBI Gene Symbol
GNLY
Protein Name
Granulysin
Gene Name URL
GNLY

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