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GH Protein

CAT: 0247-OPPA01813-20UGSize: 20 µgDry Ice: NoHazardous: No
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CAT#:0247-OPPA01813-20UGSize:20 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Gene Aliases
GH
Gene ID
280804
Accession Number
NP_851339.1
Reactivity
Bovine
Target
GH is a member of the somatotropin/prolactin family of hormones which play an important role in growth control. The gene, along with four other related genes, is located at the growth hormone locus on chromosome 17 where they are interspersed in the same transcriptional orientation; an arrangement which is thought to have evolved by a series of gene duplications. The five genes share a remarkably high degree of sequence identity. Alternative splicing generates additional isoforms of each of the five growth hormones, leading to further diversity and potential for specialization. This particular family member is expressed in the pituitary but not in placental tissue as is the case for the other four genes in the growth hormone locus. Mutations in or deletions of the gene lead to growth hormone deficiency and short stature.
Type
Protein
Source
E. coli
Sequence
Afpamslsgl fanavlraqh lhqlaadtfk efertyipeg qrysiqntqv afcfsetmpa ptgkneaqqk sdlellrisl lliqswlgpl qflsrvftns lvfgtsdrvy eklkdleegi lalmreledg tprrgqilkq tydkfdtnmr sddallknyg llscfrkdlh ktetylrvmk crrfgeasca f
Purification
The GH Bovine Recombinant is purified by proprietary chromatographic techniques.
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Concentration
1 mg/ml (prior to lyophilization)
Bioactivity
The activity as determined by the PDFP13B9 cells stably transfected with rabbit GH receptors. Bovine GH is also capable of forming a 1:2 complex with the recombinant ovine growth hormone receptor extracellular domain (ECD) .
Format
Lyophilized// 4.5mM NaHCO3 (pH 8.9) 3
Reconstitution
32
Molecular Weight
22 kDa
Notes
Formerly GWB-C4A651
Protein Length
Recombinant
NCBI Gene Symbol
BGH
Protein Name
Somatotropin
Gene Name URL
BGH

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