CALM2 Protein

• Gene Aliases:

  CaM, CAM2, CAM3, CAMB, CAMC, CAMI, PHKD, CPVT4, DD132, LQT14, CALML2, CAMIII

• Gene ID:

  801

• Accession Number:

  NP_001159578.1

• Reactivity:

  Human

• Target:

  Calmodulin-2 acts as an intracellular calcium sensor protein. When the intracellular Ca2+ concentration increases, calmodulin can bind up to four Ca2+, changing its conformation and regulating cellular functions such as activation or inhibition of a large number of enzymes, ion channels, and receptors. P53 protein stimulates CALM2 gene expression in 041 cells. CALM-2 is involved in the processes of Ca (2+) -induced neuronal cell death and the blockage of calmodulin attenuates brain injury after cerebral ischemia. Calmodulin-2 mediates the control of a large number of enzymes and other proteins by ca (2+) . among the enzymes to be stimulated by the calmodulin-ca (2+) complex are a number of protein kinases and phosphatases. Recombinant CALM2 produced in E.Coli is a single, non-glycosylated polypeptide chain containing 149 amino acids.

• Type:

  Protein

• Purification:

  CALM2 is purified by conventional chromatography techniques

• Assay Protocol:

  Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

• Concentration:

  1 mg/ml

• Format:

  Liquid//contains 20mM Tris-HCl (pH 7.5) Physical Appearance: //Sterile filtered colorless solutionPhysical Appearance: //Sterile filtered colorless solution

• Reconstitution:

  Store at 4C if entire vial will be used within 2-4 weeks. Store, frozen at -20C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA) . Avoid multiple freeze-thaw cycles.

• Molecular Weight:

  16 kDa

• Notes:

  Formerly GWB-441D60

• Protein Length:

  Recombinant

• NCBI Gene Symbol:

  CALM2

• Host or Source:

  E. Coli

• Protein Name:

  CALM1 protein EMBL AAH07965.1

• Gene Name URL:

  CALM2