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Bax Protein

CAT: 0247-OPPA01324-2UGSize: 2 µgDry Ice: NoHazardous: No
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CAT#:0247-OPPA01324-2UGSize:2 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Gene Aliases
Apoptosis regulator BAX membrane isoform alpha, Bax, Bcl2-associated X protein, Bax Mouse, Bax Mouse Recombinant
Gene ID
12028
Accession Number
NP_031553.1
Reactivity
Mouse
Target
Bcl-2 - associated X protein (Bax) belongs to the Bcl-2 protein family. Bax is a pro-apoptotic Bcl-2 protein containing BH1, BH2 and BH3 domains. Bax accelerates programmed cell death by binding to, and antagonizing the apoptosis repressor bcl2 or its adenovirus homolog e1b 19k protein. Bax induces the release of cytochrome c, activation of casp3, and thereby apoptosis. Bax is expressed in a wide variety of tissues, with highest levels in the testis and ovary. Tumor suppressor protein p53 upregulates the expression of BAX. Bax has been shown to be involved in p53-mediated apoptosis.
Type
Protein
Purification
The Mouse Bax is purified by proprietary chromatographic techniques.
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Format
The protein contains 10mM Tris-HCL pH-8, 1mM EDTA and 250mM NaCl. Physical appearance: Sterile Filtered colorless solution.
Reconstitution
Mouse Bax although stable at 12C for 1 week, should be stored desiccated below -18C. Please prevent freeze-thaw cycles.
Notes
Formerly GWB-D07CDA
Protein Length
Recombinant
NCBI Gene Symbol
MBAX
Host or Source
E. Coli
Protein Name
Apoptosis regulator BAX
Gene Name URL
MBAX

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