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TRIM21 Protein

CAT: 0247-OPPA01243-5UGSize: 5 µgDry Ice: NoHazardous: No
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CAT#:0247-OPPA01243-5UGSize:5 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Gene Aliases
SSA, RO52, SSA1, RNF81, Ro/SSA
Gene ID
6737
Accession Number
NP_003132.2
Reactivity
Human
Target
TRIM21 is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein is part of the RoSSA ribonucleoprotein, which includes a single polypeptide and one of four small RNA molecules. The RoSSA particle localizes to both the cytoplasm and the nucleus. Ro/SSA interacts with autoantigens in patients with Sjogren syndrome and systemic lupus erythematosus. Ribonucleoprotein particle is composed of a single polypeptide and one of four small RNA molecules. The RoSSA is present in all mammalian cells studied but has no known function. At least 2 isoforms are present in nucleated and red blood cells, and tissue specific differences in Ro/SSA proteins were identified.
Type
Protein
Source
Sf9 Insect Cells
Sequence
MASAARLTMMWEEVTCPICLDPFVEPVSIECGHSFCQECISQVGKGGGSVCAVCRQRFLLKNLRPNRQLANMVNNLKEISQEAREGTQGERCAVHGERLHLFCEKDGKALCWVCAQSRKHRDHAMVPLEEAAQEYQEKLQVALGELRRKQELAEKLEVEIAIKRADWKKTVETQKSRIHAEFVQQKNFLVEEEQRQLQELEKDEREQLRILGEKEAKLAQQSQALQELISELDRRCHSSALELLQEVIIVLERSESWNLKDLDITSPELRSVCHVPGLKKMLRTCAVHITLDPDTANPWLILSEDRRQVRLGDTQQSIPGNEERFDSYPMVLGAQHFHSGKHYWEVDVTGKEAWDLGVCRDSVRRKGHFLLSSKSGFWTIWLWNKQKYEAGTYPQTPLHLQVPPCQVGIFLDYEAGMVSFYNITDHGSLIYSFSECAFTGPLRPFFSPGFNDGGKNTAPLTLCPLNIGSQGSTDY.
Purification
Purified by proprietary chromatographic techniques.
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Concentration
0.99 mg/ml
Format
Liquid.// 20mM HEPES pH 7.5, 0.01mM EDTA and 0.02% SDS. Physical Appearance:// Sterile filtered clear solutionPhysical Appearance:// Sterile filtered clear solution
Reconstitution
Store at 4° C if entire vial will be used within 2-4 weeks. Store frozen at -20° C for longer periods of time. Avoid multiple freeze-thaw cycles.
Molecular Weight
52 kDa
Notes
Formerly GWB-A0D7AF
Protein Length
Recombinant
NCBI Gene Symbol
TRIM21
Protein Name
E3 ubiquitin-protein ligase TRIM21
Gene Name URL
TRIM21

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Alternative Products

CatalogName
314266-01E3 Ubiquitin-Protein ligase TRIM21 (Trim21)
abx650878-01Rat E3 Ubiquitin-Protein Ligase TRIM21 (TRIM21) Protein
abx650326-01Human E3 Ubiquitin-Protein Ligase TRIM21 (TRIM21) Protein
abx650327-01Mouse E3 Ubiquitin-Protein Ligase TRIM21 (TRIM21) Protein
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314268-01E3 Ubiquitin-Protein ligase TRIM21 (Trim21) (FITC)
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