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NGB Protein

CAT: 0247-OPPA00709-2UGSize: 2 µgDry Ice: NoHazardous: No
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CAT#:0247-OPPA00709-2UGSize:2 µg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Gene Aliases
NGB, NGB Human, Neuroglobin Human Recombinant
Gene ID
58157
Accession Number
NP_067080.1
Reactivity
Human
Target
Neuroglobin, 151 amino acid residue protein, mainly expressed in vertebrate brain and retina, is a recently identified member of the globin superfamily. Augmenting O (2) supply, neuroglobin promotes survival of neurons upon hypoxic injury, potentially limiting brain damage. Moreover, neuroglobin may be a novel oxidative stress-responsive sensor for signal transduction in the brain. Neuroglobin expression is increased by neuronal hypoxia in vitro and focal cerebral ischemia in vivo, and neuronal survival after hypoxia is reduced by inhibiting neuroglobin expression with an antisense oligodeoxynucleotide and enhanced by neuroglobin overexpression.
Type
Protein
Source
E. Coli
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Format
Lyophilized// from 0.5 mg/ml in 0.05M phosphate buffer, 0.1M NaCl, pH 7.2.
Reconstitution
Add 0.2 ml of H2O and let the lyophilized pellet dissolve completely. Store lyophilized protein at -20C. Aliquot the product after reconstitution to avoid repeated freezing/thawing cycles. Reconstituted protein can be stored at 4C for a limited period of time; it does not show any change after two weeks at 4C. The lyophilized protein remains stable until the expiry date when stored at -20C.
Notes
Formerly GWB-5909A6
Specificity
The amino acid sequence of the Neuroglobin human recombinant is 100% homologous to the amino acid sequence of the human Neuroglobin.
Protein Length
Recombinant
NCBI Gene Symbol
NGB
Protein Name
Neuroglobin
Gene Name URL
NGB

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