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IL 22 Protein

CAT: 0247-OPPA00591-2UGSize: 2 µgDry Ice: NoHazardous: No
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CAT#:0247-OPPA00591-2UGSize:2 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Gene Aliases
TIFa, IL-21, IL-22, ILTIF, IL-TIF, IL-D110, zcyto18, TIFIL-23
Gene ID
50616
Accession Number
NP_065386.1
Reactivity
Human
Target
Interleukin-22 Human Recombinant produced in E.Coli is a single, non-glycosylated homodimeric polypeptide chain containing 2 x 146 amino acids.IL-22 is a member of the IL-10 family of regulatory cytokines.Members of this family share partial homology in their amino acid sequences, but they are dissimilar in their biological functions. Produced by T lymphocytes, IL-22 inhibits IL-4 production by Th2 cells, and induces acute phase reactants in the liver and pancreas. IL-22 signals through a receptor system consisting of IL-10R-beta/CRF2-4 and IL-22R, both of which are members of the class II cytokine-receptor family.
Type
Protein
Sequence
The sequence of the first five N - terminal amino acids was determined and was found to be Met - Ala - Pro - Ile - Ser.
Purification
Purified by proprietary chromatographic techniques.
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Bioactivity
The Biological Activity was determined by the ability to activate STAT following receptor ligand interaction.
Format
Lyophilized.// Each mg contains 50mM Phosphate buffer (pH 7.1) Physical Appearance:// Sterile Filtered White freeze-dried powderPhysical Appearance:// Sterile Filtered White freeze-dried powder
Reconstitution
It is recommended to reconstitute the lyophilized Interleukin -22 in sterile 18M-omega-cm H2O not less than 100 ug/ml, which can then be further diluted to other aqueous solutions. Lyophilized Interleukin-22, although stable at room temperature for 3 weeks, should be stored desiccated below -18C. Upon reconstitution IL22 should be stored at 4C between 2-7 days and for future use below -18C. Please prevent freeze-thaw cycles.
Molecular Weight
34 kDa
Notes
Formerly GWB-A992EE
Protein Length
Recombinant
NCBI Gene Symbol
IL22
Host or Source
E. Coli
Protein Name
Interleukin-22
Gene Name URL
IL22

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