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ITLN1 Recombinant Protein (Human)

CAT: 0247-OPED00109-10UGSize: 10 µgDry Ice: NoHazardous: No
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CAT#:0247-OPED00109-10UGSize:10 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
9000-83-3
Gene Name
Intelectin 1
Gene Aliases
Endothelial lectin HL-1; galactofuranose-binding lectin; hIntL; HL1; HL-1; intelectin 1 (galactofuranose binding) ; intelectin-1; intestinal lactoferrin receptor; INTL; ITLN; ITLN-1; LFR; omentin.
Gene ID
55600
Accession Number
NP_009138.1
Reactivity
Homo sapiens|Human
Target
Lectin that specifically recognizes microbial carbohydrate chains in a calcium-dependent manner (PubMed:11313366, PubMed:26148048) . Binds to microbial glycans that contain a terminal acyclic 1,2-diol moiety, including beta-linked D-galactofuranose (beta-Galf), D-phosphoglycerol-modified glycans, D-glycero-D-talo-oct-2-ulosonic acid (KO) and 3-deoxy-D-manno-oct-2-ulosonic acid (KDO) (PubMed:26148048) . Binds to glycans from Gram-positive and Gram-negative bacteria, including K.pneumoniae, S.pneumoniae, Y.pestis, P.mirabilis and P.vulgaris (PubMed:26148048) . Does not bind human glycans (PubMed:26148048) . Probably plays a role in the defense system against microorganisms (Probable) . May function as adipokine that has no effect on basal glucose uptake but enhances insulin-stimulated glucose uptake in adipocytes (PubMed:16531507) . Increases AKT phosphorylation in the absence and presence of insulin (PubMed:16531507) . May interact with lactoferrin/LTF and increase its uptake, and may thereby play a role in iron absorption (PubMed:11747454, PubMed:23921499) .
Type
Protein
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Format
Lyophilized. Contains PBS.
Reconstitution
Reconstitute with 100 ul sterile water. PBS containing at least 0.1% BSA should be used for further dilutions. Store at -20C
Molecular Weight
40 kDa
Protein Length
Recombinant
NCBI Gene Symbol
ITLN1
Host or Source
HEK 293 cells
Protein Name
Intelectin-1
Gene Name URL
ITLN1
Nucleotide Accession Number
NM_007207.5