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DUSP6 Recombinant Protein (Human)

CAT: 0247-OPED00087-100UGSize: 100 µgDry Ice: NoHazardous: No
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CAT#:0247-OPED00087-100UGSize:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
9000-83-3
Gene Name
Dual specificity phosphatase 6
Gene Aliases
Dual specificity protein phosphatase 6; dual specificity protein phosphatase PYST1; HH19; MAP kinase phosphatase 3; mitogen-activated protein kinase phosphatase 3; MKP3; PYST1; serine/threonine specific protein phosphatase.
Gene ID
1848
Accession Number
NP_004647.1
Reactivity
Homo sapiens|Human
Target
Inactivates MAP kinases. Has a specificity for the ERK family (PubMed:9858808) . Plays an important role in alleviating chronic postoperative pain. Necessary for the normal dephosphorylation of the long-lasting phosphorylated forms of spinal MAPK1/3 and MAP kinase p38 induced by peripheral surgery, which drives the resolution of acute postoperative allodynia (By similarity) . Also important for dephosphorylation of MAPK1/3 in local wound tissue, which further contributes to resolution of acute pain (By similarity) .
Type
Protein
Purification
Partially purified by single-step affinity chromatography and gel filtration.
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Format
Liquid. In 20mM TRIS/HCl, pH 8.0, 200mM NaCl, 5mM DTT, 0.1 % Tween-20, 10% glycerol.
Reconstitution
Store at -80C
Molecular Weight
42 kDa
Protein Length
Recombinant
NCBI Gene Symbol
DUSP6
Host or Source
Sf9 cells
Protein Name
Dual specificity protein phosphatase 6
Gene Name URL
DUSP6
Nucleotide Accession Number
NM_004656.3

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