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HDAC6 Recombinant Protein (Human)

CAT: 0247-OPED00058-50UGSize: 50 µgDry Ice: NoHazardous: No
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CAT#:0247-OPED00058-50UGSize:50 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
9000-83-3
Gene Name
Histone deacetylase 6
Gene Aliases
CPBHM; HD6; histone deacetylase 6; JM21; PPP1R90; protein phosphatase 1, regulatory subunit 90; tubulin-lysine deacetylase HDAC6.
Gene ID
10013
Accession Number
NP_001035930.1
Reactivity
Homo sapiens|Human
Target
Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4) . Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes (By similarity) . Plays a central role in microtubule-dependent cell motility via deacetylation of tubulin. Involved in the MTA1-mediated epigenetic regulation of ESR1 expression in breast cancer.
Type
Protein
Purification
Partially purified by single-step affinity chromatography and gel filtration.
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Format
Liquid. In 50mM TRIS, pH 8.0, 138 mM NaCl and 10% glycerol.
Reconstitution
Store at -80C
Molecular Weight
131 kDa
Protein Length
Recombinant
NCBI Gene Symbol
HDAC6
Host or Source
Insect cells
Protein Name
Histone deacetylase 6
Gene Name URL
HDAC6
Nucleotide Accession Number
NM_001042465.2

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