SFRP1 Recombinant Protein

• Gene Name:

  Secreted frizzled related protein 1

• Gene Aliases:

  Frizzled-related protein; FRP; FRP1; FRP-1; FrzA; SARP2; SARP-2; secreted apoptosis-related protein 2; secreted frizzled-related protein 1; sFRP-1.

• Gene ID:

  6422

• Accession Number:

  NP_003003.3

• Reactivity:

  Homo sapiens|Human

• Target:

  Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP1 decreases intracellular beta-catenin levels (By similarity) . Has antiproliferative effects on vascular cells, in vitro and in vivo, and can induce, in vivo, an angiogenic response. In vascular cell cycle, delays the G1 phase and entry into the S phase (By similarity) . In kidney development, inhibits tubule formation and bud growth in metanephroi (By similarity) . Inhibits WNT1/WNT4-mediated TCF-dependent transcription.

• Conjugation:

  Unconjugated

• Type:

  Protein

• Source:

  E.coli

• Applications:

  Positive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot

• Assay Protocol:

  Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

• Concentration:

  50 ug/mL (prior to lyoph)

• Format:

  Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.

• Reconstitution:

  2°C to 8°C|-80°C

• Molecular Weight:

  38kDa

• Protein Length:

  Recombinant

• NCBI Gene Symbol:

  SFRP1

• Host or Source:

  E.coli

• Protein Name:

  Secreted frizzled-related protein 1

• Gene Name URL:

  SFRP1

• CAS Number:

  9000-83-3

• Nucleotide Accession Number:

  NM_003012.4