NOS2 Recombinant Protein

• Gene Name :

  Nitric oxide synthase 2, inducible

• Gene Aliases :

  Inducible nitric oxide synthase; inducible NO synthase; inducible NOS; iNOS; i-NOS; MAC-NOS; macrophage NOS; N; nitric oxide synthase 2, inducible, macrophage; nitric oxide synthase, inducible; No; NOS type II; Nos-2; Nos2a; NOS-II; peptidyl-cysteine S-nitrosylase NOS2.

• Gene ID :

  18126

• Accession Number :

  NP_001300850.1

• Reactivity :

  Mouse|Mus musculus

• Target :

  Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body (PubMed:7503239) . In macrophages, NO mediates tumoricidal and bactericidal actions. Also has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such PTGS2/COX2 (PubMed:16373578) . As component of the iNOS-S100A8/9 transnitrosylase complex involved in the selective inflammatory stimulus-dependent S-nitrosylation of GAPDH implicated in regulation of the GAIT complex activity and probably multiple targets including ANXA5, EZR, MSN and VIM (By similarity) . Involved in inflammation, enhances the synthesis of proinflammatory mediators such as IL6 and IL8 (By similarity) .

• Conjugation :

  Unconjugated

• Type :

  Protein

• Source :

  E.coli

• Applications :

  Positive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot

• Assay Protocol :

  Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

• Concentration :

  200 ug/mL (prior to lyoph)

• Format :

  Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.

• Reconstitution :

  2°C to 8°C|-80°C

• Molecular Weight :

  10kDa

• Protein Length :

  Recombinant

• NCBI Gene Symbol :

  Nos2

• Host or Source :

  E.coli

• Protein Name :

  Nitric oxide synthase, inducible

• Gene Name URL :

  Nos2

• CAS Number :

  9000-83-3

• Nucleotide Accession Number :

  NM_001313921.1