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NOS2 Recombinant Protein

CAT: 0247-OPCD05731-200UGSize: 200 µgDry Ice: NoHazardous: No
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CAT#:0247-OPCD05731-200UGSize:200 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
9000-83-3
Gene Name
Nitric oxide synthase 2, inducible
Gene Aliases
Inducible nitric oxide synthase; inducible NO synthase; inducible NOS; iNOS; i-NOS; MAC-NOS; macrophage NOS; N; nitric oxide synthase 2, inducible, macrophage; nitric oxide synthase, inducible; No; NOS type II; Nos-2; Nos2a; NOS-II; peptidyl-cysteine S-nitrosylase NOS2.
Gene ID
18126
Accession Number
NP_001300850.1
Reactivity
Mouse|Mus musculus
Target
Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body (PubMed:7503239) . In macrophages, NO mediates tumoricidal and bactericidal actions. Also has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such PTGS2/COX2 (PubMed:16373578) . As component of the iNOS-S100A8/9 transnitrosylase complex involved in the selective inflammatory stimulus-dependent S-nitrosylation of GAPDH implicated in regulation of the GAIT complex activity and probably multiple targets including ANXA5, EZR, MSN and VIM (By similarity) . Involved in inflammation, enhances the synthesis of proinflammatory mediators such as IL6 and IL8 (By similarity) .
Conjugation
Unconjugated
Type
Protein
Source
E.coli
Applications
Positive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Concentration
200 ug/mL (prior to lyoph)
Format
Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
Reconstitution
2°C to 8°C|-80°C
Molecular Weight
10kDa
Protein Length
Recombinant
NCBI Gene Symbol
Nos2
Host or Source
E.coli
Protein Name
Nitric oxide synthase, inducible
Gene Name URL
Nos2
Nucleotide Accession Number
NM_001313921.1

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