MMP14 Recombinant Protein

• Gene Name:

  Matrix metallopeptidase 14 (membrane-inserted)

• Gene Aliases:

  AI325305; matrix metalloproteinase 14 (membrane-inserted) ; matrix metalloproteinase-14; Membrane type 1-MMP; Membrane-type matrix metalloproteinase 1; membrane-type-1 matrix metalloproteinase; MMP-X1; MT1-MM; MT1-MMP; MT-MMP; MT-MMP-1; sa; sabe; type 1 matrix metalloprotease 14.

• Gene ID:

  17387

• Accession Number:

  NP_032634.3

• Reactivity:

  Mouse|Mus musculus

• Target:

  Endopeptidase that degrades various components of the extracellular matrix such as collagen. Activates progelatinase A. Essential for pericellular collagenolysis and modeling of skeletal and extraskeletal connective tissues during development (PubMed:10520996) . May be involved in actin cytoskeleton reorganization by cleaving PTK7 (By similarity) . Acts as a positive regulator of cell growth and migration via activation of MMP15. Involved in the formation of the fibrovascular tissues (By similarity) . Cleaves ADGRB1 to release vasculostatin-40 which inhibits angiogenesis (By similarity) .

• Conjugation:

  Unconjugated

• Type:

  Protein

• Source:

  E.coli

• Applications:

  Positive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot

• Assay Protocol:

  Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

• Concentration:

  200 ug/mL (prior to lyoph)

• Format:

  Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.

• Reconstitution:

  2°C to 8°C|-80°C

• Molecular Weight:

  44kDa

• Protein Length:

  Recombinant

• NCBI Gene Symbol:

  Mmp14

• Protein Name:

  Matrix metalloproteinase-14

• Gene Name URL:

  Mmp14

• CAS Number:

  9000-83-3

• Nucleotide Accession Number:

  NM_008608.4