HSD17B10 Recombinant Protein
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HSD17B10 Recombinant Protein
Gene Aliases:
17-beta-hydroxysteroid dehydrogenase 10;3-hydroxy-2-methylbutyryl-CoA dehydrogenase;3-hydroxyacyl-CoA dehydrogenase type II; Endoplasmic reticulum-associated amyloid beta-peptide-binding protein; Mitochondrial ribonuclease P protein 2; Type II HADH.Reactivity:
Mouse|Mus musculusTarget:
Mitochondrial dehydrogenase that catalyzes the beta-oxidation at position 17 of androgens and estrogens and has 3-alpha-hydroxysteroid dehydrogenase activity with androsterone (By similarity) . Catalyzes the third step in the beta-oxidation of fatty acids (By similarity) . Carries out oxidative conversions of 7-alpha-OH and 7-beta-OH bile acids (By similarity) . Also exhibits 20-beta-OH and 21-OH dehydrogenase activities with C21 steroids (By similarity) . By interacting with intracellular amyloid-beta, it may contribute to the neuronal dysfunction associated with Alzheimer disease (AD) (By similarity) . Essential for structural and functional integrity of mitochondria (PubMed:20077426) .Conjugation:
UnconjugatedType:
ProteinSource:
E.coliApplications:
Positive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blotAssay Protocol:
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) ProtocolConcentration:
200 ug/mL (prior to lyoph)Format:
Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.Reconstitution:
2°C to 8°C|-80°CMolecular Weight:
24kDaProtein Length:
RecombinantNCBI Gene Symbol:
HSD17B10Host or Source:
E.coliProtein Name:
3-hydroxyacyl-CoA dehydrogenase type-2Gene Name URL:
HSD17B10CAS Number:
9000-83-3
