CDH5 Recombinant Protein

• Gene Name :

  Cadherin 5

• Gene Aliases :

  7B4;7B4 antigen; cadherin 5, type 2 (vascular endothelium) ; cadherin 5, type 2, VE-cadherin (vascular epithelium) ; cadherin-5; CD144; cd144 antigen; endothelial-specific cadherin; vascular endothelial cadherin; VE-cadherin.

• Gene ID :

  1003

• Accession Number :

  NP_001786.2

• Reactivity :

  Homo sapiens|Human

• Target :

  Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. This cadherin may play a important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions. It associates with alpha-catenin forming a link to the cytoskeleton. Acts in concert with KRIT1 to establish and maintain correct endothelial cell polarity and vascular lumen. These effects are mediated by recruitment and activation of the Par polarity complex and RAP1B. Required for activation of PRKCZ and for the localization of phosphorylated PRKCZ, PARD3, TIAM1 and RAP1B to the cell junction.

• Conjugation :

  Unconjugated

• Type :

  Protein

• Source :

  E.coli

• Applications :

  Positive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot

• Assay Protocol :

  Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

• Concentration :

  200 ug/mL (prior to lyoph)

• Format :

  Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.

• Reconstitution :

  2°C to 8°C|-80°C

• Molecular Weight :

  40kDa

• Protein Length :

  Recombinant

• NCBI Gene Symbol :

  CDH5

• Host or Source :

  E.coli

• Protein Name :

  Cadherin-5

• Gene Name URL :

  CDH5

• CAS Number :

  9000-83-3

• Nucleotide Accession Number :

  NM_001795.4