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CCL19 Protein

CAT: 0247-OPCB00011-5UGSize: 5 µgDry Ice: NoHazardous: No
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CAT#:0247-OPCB00011-5UGSize:5 µg
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Gene Name
Chemokine (C-C motif) ligand 19
Gene Aliases
ELC, CKb11, MIP3B, MIP-3b, SCYA19
Gene ID
6363
Target
Macrophage inflammatory protein-3-beta (MIP3Β ) (CCL19), also known as EBI1 ligand chemokine (ELC), directs chemotaxis of dendritic cells, and certain B- and T- lymphocytes, but not monocytes or granulocytes. It is constitutively expressed in thymus and lymph nodes and binds specifically to target cells expressing the receptor CCR7. Being a homeostatic chemokine, its primary physiological role is considered to be in the normal recirculation and homing of lymphocyte. However, MIP3beta could also be proinfammatory, and is implicated in the post-HIV infection responses.
Type
Protein
Source
E. coli
Applications
CA
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Bioactivity
EC50 = 7.0 nM determined by Migration Assay with recombinant human CCR7
Format
Lyophilized//
Molecular Weight
8.800 kDa
Protein Length
22-98
NCBI Gene Symbol
CCL19
Gene Name URL
CCL19