CCL3 Protein

• Gene Name:

  Chemokine (C-C motif) ligand 3

• Gene Aliases:

  MIP1A, SCYA3, G0S19-1, LD78ALPHA, MIP-1-alpha

• Gene ID:

  6348

• Target:

  Macrophage inflammatory proteins 1-alpha (MIP1alpha) (CCL3) binds to cell surface receptors CCR1 and CCR5. It is proinflammatory, leading to chemotaxis and activation of immune cells. It also inhibits proliferation of hematopoietic stem cells. Moreover, by binding to one of the HIV coreceptors, CCR5, it suppresses HIV infection.

• Type:

  Protein

• Source:

  E. coli

• Applications:

  CA

• Assay Protocol:

  Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

• Bioactivity:

  EC50 = 0.2 nM determined by Migration Assay in cells expressing recombinant CCR5

• Format:

  Lyophilized

• Reconstitution:

  Shipping: //Room Temp

• Molecular Weight:

  7.716 kDa

• NCBI Gene Symbol:

  CCL3

• Gene Name URL:

  CCL3