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LAMTOR3 Recombinant Protein (Human)

CAT: 0247-OPCA04786-100UGSize: 100 µgDry Ice: NoHazardous: No
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CAT#:0247-OPCA04786-100UGSize:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
9000-83-3
Gene Name
Late endosomal/lysosomal adaptor, MAPK and MTOR activator 3
Gene Aliases
Late endosomal/lysosomal adaptor and MAPK and MTOR activator 3; MAP2K1IP1; MAPBP; MAPK scaffold protein 1; MAPKSP1; MEK binding partner 1; MEK-binding partner 1; mitogen-activated protein kinase kinase 1 interacting protein 1; Mitogen-activated protein kinase kinase 1-interacting protein 1; mitogen-activated protein kinase scaffold protein 1; MP1; PRO0633; ragulator complex protein LAMTOR3; Ragulator3.
Gene ID
8649
Accession Number
NP_001230665
Reactivity
Homo sapiens|Human
Target
As part of the Ragulator complex it is involved in amino acid sensing and activation of mTORC1, a signaling complex promoting cell growth in response to growth factors, energy levels, and amino acids. Activated by amino acids through a mechanism involving the lysosomal V-ATPase, the Ragulator functions as a guanine nucleotide exchange factor activating the small GTPases Rag. Activated Ragulator and Rag GTPases function as a scaffold recruiting mTORC1 to lysosomes where it is in turn activated. Adapter protein that enhances the efficiency of the MAP kinase cascade facilitating the activation of MAPK2.
Type
Protein
Source
E.coli
Sequence
MADDLKRFLYKKLPSVEGLHAIVVSDRDGVPVIKVANDNAPEHALRPGFLSTFALATDQGSKLGLSKNKSIICYYNTYQVVQFNRLPLVVSFIASSSANTGLIVSLEKELAPLFEELRQVVEVS
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Format
Liquid or Lyophilized powder
Buffer
If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
Reconstitution
-20°C or -80°C
Molecular Weight
40.6 kDa
Protein Length
Recombinant
NCBI Gene Symbol
LAMTOR3
Protein Name
Ragulator complex protein LAMTOR3
Gene Name URL
LAMTOR3
Nucleotide Accession Number
NM_001243736

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Alternative Products

CatalogName
CSB-EP013477HU-01Recombinant Human Ragulator complex protein LAMTOR3 (LAMTOR3)
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BLT-04902P-01Human LAMTOR3 (Ragulator Complex Protein Lamtor3) - Recombinant Protein
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PPT-13622Human LAMTOR3 Recombinant Protein
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P6917-01Recombinant Human LAMTOR3
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