IFNAR2 Recombinant Protein (Human)

• Gene Name:

  Interferon alpha and beta receptor subunit 2

• Gene Aliases:

  Human interferon alpha/beta receptor; IFNABR; IFN-alpha/beta receptor 2; IFNalpha/beta receptor subunit 2; IFN-alpha-REC; IFNARB; IFN-R; IFN-R-2; IMD45; interferon (alpha, beta and omega) receptor 2; interferon alpha binding protein; interferon alpha/beta receptor 2; interferon receptor; interferon-alpha/beta receptor beta chain; type I interferon receptor 2.

• Gene ID:

  3455

• Accession Number:

  NP_000865

• Reactivity:

  Homo sapiens|Human

• Target:

  Associates with IFNAR1 to form the type I interferon receptor. Receptor for interferons alpha and beta. Involved in IFN-mediated STAT1, STAT2 and STAT3 activation (PubMed:26424569) . Isoform 1 and isoform 2 are directly involved in signal transduction due to their association with the TYR kinase, JAK1 (PubMed:8181059, PubMed:7665574, PubMed:7759950) . Isoform 3 is a potent inhibitor of type I IFN receptor activity (PubMed:7759950) .

• Type:

  Protein

• Source:

  E.coli

• Sequence:

  ISYDSPDYTDESCTFKISLRNFRSILSWELKNHSIVPTHYTLLYTIMSKPEDLKVVKNCANTTRSFCDLTDEWRSTHEAYVTVLEGFSGNTTLFSCSHNFWLAIDMSFEPPEFEIVGFTNHINVMVKFPSIVEEELQFDLSLVIEEQSEGIVKKHKPEIKGNMSGNFTYIIDKLIPNTNYCVSVYLEHSDEQAVIKSPLKCTLLPPGQESESAESAK

• Assay Protocol:

  Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

• Format:

  Liquid or Lyophilized powder

• Buffer:

  If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.

• Reconstitution:

  -20°C or -80°C

• Molecular Weight:

  40.8 kDa

• Protein Length:

  Recombinant

• NCBI Gene Symbol:

  IFNAR2

• Protein Name:

  Interferon alpha/beta receptor 2

• Gene Name URL:

  IFNAR2

• CAS Number:

  9000-83-3

• Nucleotide Accession Number:

  NM_000874