SR9243

CAT: 0804-HY-16972-04Size: 25 mgDry Ice: NoHazardous: No

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CAT#:0804-HY-16972-04Size:25 mg

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Description

SR9243 is a liver-X-receptor (LXR) inverse agonist that induces LXR-corepressor interaction.

CAS Number

1613028-81-1

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

LXR

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/SR9243.html

Purity

98.88

Solubility

DMSO : 20 mg/mL (ultrasonic)

Smiles

BrC1=CC(CCN(S(C2=C(C)C=C(C)C=C2C)(=O)=O)CC(C=C3)=CC=C3C4=CC(S(=O)(C)=O)=CC=C4)=CC=C1

Molecular Formula

C31H32BrNO4S2

Molecular Weight

626.62

Precautions

H302, H315, H319, H335

References & Citations

[1]Flaveny CA, et al. Broad Anti-tumor Activity of a Small Molecule that Selectively Targets the Warburg Effect and Lipogenesis. Cancer Cell. 2015 Jun 24. pii: S1535-6108 (15) 00183-X.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Chemical Information

SR9243

SR9243 is a sulfonamide resulting from the formal condensation of the sulfonic acid group of mesitylene-2-sulphonic acid with the amino group of 2-(m-bromophenyl)ethylamine in which the nitrogen is substituted by a 4-[m-(methylsulfonyl)phenyl]benzyl group. It has a role as an antineoplastic agent, an apoptosis inducer and a liver X receptor inverse agonist. It is a sulfonamide, a sulfone and a member of bromobenzenes.

CAS Number	1613028-81-1
PubChem CID	76073169
IUPAC Name	N-[2-(3-bromophenyl)ethyl]-2,4,6-trimethyl-N-[[4-(3-methylsulfonylphenyl)phenyl]methyl]benzenesulfonamide
Molecular Formula	C31H32BrNO4S2
Molecular Weight	626.6
XLogP	7.2
Topological Polar Surface Area	88.3
Hydrogen Bond Donor Count	0
Hydrogen Bond Acceptor Count	5
Rotatable Bond Count	9
Heavy Atom Count	39
Formal Charge	0
Complexity	971

SMILES

CC1=CC(=C(C(=C1)C)S(=O)(=O)N(CCC2=CC(=CC=C2)Br)CC3=CC=C(C=C3)C4=CC(=CC=C4)S(=O)(=O)C)C

InChI

InChI=1S/C31H32BrNO4S2/c1-22-17-23(2)31(24(3)18-22)39(36,37)33(16-15-25-7-5-9-29(32)19-25)21-26-11-13-27(14-12-26)28-8-6-10-30(20-28)38(4,34)35/h5-14,17-20H,15-16,21H2,1-4H3

InChIKey

FYQFEJFTCLKXTQ-UHFFFAOYSA-N

Chemical Structure

2D Structure

CAS: 1613028-81-1

CID: 76073169

Formula: C31H32BrNO4S2

MW: 626.6

Interactive 3D Structure

Loading 3D structure...

View on PubChem Raw 3D data

Computed Properties

Property	Value
Molecular Weight	626.6
XLogP3	7.2
Hydrogen Bond Donor Count	0
Hydrogen Bond Acceptor Count	5
Rotatable Bond Count	9
Exact Mass	625.09561
Monoisotopic Mass	625.09561
Topological Polar Surface Area	88.3 Å²
Heavy Atom Count	39
Formal Charge	0
Complexity	971
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently-Bonded Unit Count	1
Compound Is Canonicalized	Yes

Related Products

Catalog	Name
HY-101442-01	SR9238
HY-101442R-01	SR9238 (Standard)
HY-W841840-01	SR94

Alternative Products

Catalog	Name
TRC-S684475-10MG	SR9243
A15535-2	SR9243 2mg
A15535-200	SR9243 200mg
A15535-25	SR9243 25mg
A15535-10	SR9243 10mg
A15535-5	SR9243 5mg
A15535-100	SR9243 100mg

SR9243

Chemical Information

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