Products for Research Use Only
RegisterLogin

KB02-COOH

CAT: 0804-HY-131385-01Size: 5 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-131385-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
KB02-COOH is a fragment of synthesis of ubiquitin E3 ligase ligand KB02. KB02 can be used in the synthesis of PROTAC, such as KB02-JQ1 and KB02-SLF (HY-129610).
CAS Number
2375196-30-6
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Ligands for E3 Ligase
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/kb02-cooh.html
Purity
98.88
Solubility
DMSO : 66.67 mg/mL (ultrasonic)
Smiles
O=C(O)COC1=CC2=C(N(C(CCl)=O)CCC2)C=C1
Molecular Formula
C13H14ClNO4
Molecular Weight
283.71
Precautions
H302, H315, H319, H335
References & Citations
[1]Zhang X, et al. Electrophilic PROTACs that degrade nuclear proteins by engaging DCAF16. Nat Chem Biol. 2019 Jul;15 (7) :737-746.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Cereblon

Related Products

CatalogName
HY-129917-01KB02-JQ1
HY-129610-01KB02-SLF
HY-176389KB02-amide-PEG2-C2-acid
HY-163758COOH-C3-CONH-C7-COOH
HY-169236COOH-C-PEG2-NHCO-C2-COOH
HY-130979-01EED226-COOH
HY-136596-01Apalutamide-COOH
HY-D1345-01SiR-COOH
HY-160429-01PSAR18-COOH
HY-153013-01SN38-COOH

Alternative Products

CatalogName
T39923-01KB02-COOH
BA4698-1KB02-JQ1
JVD18440-01KB02-SLF
GTR19265523-01KB02-amide-PEG2-C2-acid
MD016016-5-01COOH-PEG5-COOH
MD016016-3-01COOH-PEG3-COOH
MD016016-2-01COOH-PEG2-COOH
MD016016-16COOH-PEG16-COOH
MD016016-8COOH-PEG8-COOH
MD016016-6COOH-PEG6-COOH

Popular Products