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HX1

CAT: 0804-HY-116188Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-116188Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
HX1 is a potent reversible myeloperoxidase (MPO) inhibitor with an IC50 value of 50 nM. HX1 is bound within the active site cavity above the heme and blocks the substrate channel. HX1 is promising for research of inflammatory diseases[1].
CAS Number
1520083-61-7
UNSPSC
12352005
Hazard Statement
H302-H312-H315-H319-H332-H335
Type
Reference compound
Related Pathways
Others
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/hx1.html
Smiles
O=C(C1=CN=C(NCC2=CC(C(F)(F)F)=CC(C(F)(F)F)=C2)NC1=O)NO
Molecular Formula
C14H10F6N4O3
Molecular Weight
396.24
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362-P403+P233-P405-P501
References & Citations
[1]Forbes LV, et al. Potent reversible inhibition of myeloperoxidase by aromatic hydroxamates. J Biol Chem. 2013 Dec 20;288 (51) :36636-47.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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