PDGFRA Antibody

• Gene Name:

  Platelet derived growth factor receptor alpha

• Gene Aliases:

  CD140A, PDGFR2, PDGFR-2

• Gene ID:

  5156

• Accession Number:

  NP_006197.1

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Synthetic Peptide of PDGFRalpha

• Target:

  This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies suggest that this gene plays a role in organ development, wound healing, and tumor progression. Mutations in this gene have been associated with idiopathic hypereosinophilic syndrome, somatic and familial gastrointestinal stromal tumors, and a variety of other cancers.

• Clonality:

  Monoclonal

• Type:

  Monoclonal Antibody

• Applications:

  IHC

• Purification:

  The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.

• Assay Protocol:

  Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

• Concentration:

  1 mg/ml

• Format:

  Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Reconstitution:

  Store at -20C. Avoid repeated freeze/thaw cycles.

• Fragment:

  IgG1

• Specificity:

  PDGFRalpha Mouse Monoclonal Antibody (7A3) detects endogenous levels of PDGFRA

• NCBI Gene Symbol:

  PDGFRA

• Host or Source:

  Mouse

• Protein Name:

  Platelet-derived growth factor receptor alpha

• Gene Name URL:

  PDGFRA

• CAS Number:

  9007-83-4

• Nucleotide Accession Number:

  NM_006206.4